您好,欢迎访问华体会网站!
您好,欢迎访问华体会网站!
集团动态
联系华体会
发布日期:2024-07-25 作者:华体会
Science,5JUL2024,VOL385,ISSUE6704
《科学》2024年7月5日,第385卷,6704期
材料科学MaterialsScience
Developingfatigue-resistantferroelectricsusinginterlayerslidingswitching
操纵层间滑动开关开辟耐疲惫铁电体
▲作者:RENJIBIAN,RIHEetal.
▲链接:
https://www.science.org/doi/10.1126/science.ado1744
▲摘要:
我们陈述一种基在双层3R-MoS2滑动铁电的无疲惫铁电系统。这类铁电器件的记忆机能在低周期时不表示出叫醒效应,在分歧脉宽下106个开关周期后也不表示出较着的疲惫效应。
这类器件在电场感化下的总应力时候可达105s,相对其他器件而言,这是一个较长的应力时候。我们的理论计较注解,滑动铁电的无疲惫特征是因为滑动铁电中的固定电荷缺点酿成的。
▲Abstract:
Wereportafatigue-freeferroelectricsystembasedontheslidingferroelectricityofbilayer3Rmolybdenumdisulfide(3R-MoS2).Thememoryperformanceofthisferroelectricdevicedoesnotshowthewake-upeffectatlowcyclesorasubstantialfatigueeffectafter106switchingcyclesunderdifferentpulsewidths.Thetotalstresstimeofthedeviceunderanelectricfieldisupto105s,whichislongrelativetootherdevices.Ourtheoretica华体会体育applcalculationsrevealthatthefatigue-freefeatureofslidingferroelectricityisduetotheimmobilechargedefectsinslidingferroelectricity.
Aphotoluminescenthydrogen-bondedbiomassaerogelforsustainableradiativecooling
用在可延续辐射冷却的光致发光氢键生物资气凝胶
▲作者:JIAN-WENMA,FU-RONGZENGetal.
▲链接:
https://www.science.org/doi/10.1126/science.adn5694
▲摘要:
我们展现一种本征光致发光生物资气凝胶,其可见光反射率跨越100%,可以发生很强的冷却结果。我们发现,DNA和明胶堆积成有序的层状气凝胶,经由过程荧光和磷光在可见光区到达104.0%的太阳加权反射率。在高太阳辐照度下,该材料的冷却结果可以使情况温度下降16.0℃。
另外,这类能经由过程水焊高效批量出产的气凝胶具有很高的可修复性、可收受接管性和可生物降解性,构成环保的轮回进程。这类生物资光致发光材料或成为设计下一代可延续冷却材料的一种路子。
▲Abstract:
Wepresentanintrinsicphotoluminescentbiomassaerogel,whichhasavisiblelightreflectanceexceeding100%,thatyieldsalargecoolingeffect.WediscoveredthatDNAandgelatinaggregationintoanorderedlayeredaerogelachievesasolar-weightedreflectanceof104.0%invisiblelightregionsthroughfluorescenceandphosphorescence.Thecoolingeffectcanreduceambienttemperaturesby16.0°Cunderhighsolarirradiance.Inaddition,theaerogel,efficientlyproducedatscalethroughwater-welding,displayshighreparability,recyclability,andbiodegradability,completinganenvironmentallyconsciouslifecycle.Thisbiomassphotoluminescencematerialisanothertoolfordesigningnext-generationsustainablecoolingmaterials.
Wignermolecularcrystalsfrommultielectronmoiréartificialatoms
多电子莫尔人工原子制备的维格纳份子晶体
▲作者:HONGYUANLI,ZIYUXIANGetal.
▲链接:
https://www.science.org/doi/10.1126/science.adk1348
▲摘要:
在此,我们陈述在扭曲双层二硫化钨莫尔维尔超晶格中由多电子人工原子构成的维格纳份子晶体的尝试不雅察。操纵扫描地道显微镜,我们证实了当库仑彼此感化占主导地位时,多电子人造原子中会呈现维格纳份子。
在超晶格中不雅察到的维格纳份子阵列包罗电子的结晶相:维格纳份子晶体,经由过程机械应变、莫尔周期和载流子电荷类型显示出高度可调。
▲Abstract:
HerewereporttheexperimentalobservationofWignermolecularcrystalsemergingfrommultielectronartificialatomsintwistedbilayertungstendisulfidemoirésuperlattices.Usingscanningtunnelingmicroscopy,wedemonstratethatWignermoleculesappearinmultielectronartificialatomswhenCoulombinteractionsdominate.ThearrayofWignermoleculesobservedinamoirésuperlatticecomprisesacrystallinepha搜索引擎优化felectrons:theWignermolecularcrystal,whichisshowntobehighlytunablethroughmechanicalstrain,moiréperiod,andcarrierchargetype.
生态学Ecology
Treeshaveoverlappingpotentialnichesthatextendbeyondtheirrealizedniches
树的堆叠潜伏生态位跨越现实生态位
▲作者:DANIELC.LAUGHLINANDBRIANJ.MCGILL
▲链接:
https://www.science.org/doi/10.1126/science.adm8671
▲摘要:
树种仿佛会偏向在分歧的天气前提,但这类偏向遭到物种相互感化和分散的限制,从而限制了物种的散布规模。我们量化了188种北美树种的现实和潜伏热生态位,对生态位的布局进行了年夜陆范围的测试。
我们发现了强有力且一致的证据,注解极端温度下的物种占有了不到四分之三的潜伏生态位,而在年平均温度12度摆布时,物种的潜伏生态位会堆叠。这些成果说明了温带树种的热耐受广度,并撑持了热生态位的离心组织。斟酌生态位的潜伏构成可以增进全球转变生态学的理论和猜测。
▲Abstract:
Treespeciesappeartopreferdistinctclimaticconditions,butthetruenatureofthesepreferencesisobscuredbyspeciesinteractionsanddispersal,whichlimitspecies’ranges.Wequantifiedrealizedandpotentialthermalnichesof188NorthAmericantreespeciestoconductacontinental-scaletestofthearchitectureofniches.Wefoundstrongandconsistentevidencethatspeciesoccurringatthermalextremesoccupylessthanthree-quartersoftheirpotentialniches,andspecies’potentialnichesoverlapatameanannualtemperatureof~12°C.Theseresultsclarifythebreadthofthermaltolerancesoftemperatetreespeciesandsupportthecentrifugalorganizationofthermalniches.Accountingforthenonrealizedcomponentsofecologicalnicheswilladvancetheoryandpredictioninglobalchangeecology.
医学Medicine
AmoleculargluedegraderoftheWIZtranscriptionfactorforfetalhemoglobininduction
引诱胎儿血红卵白的WIZ转录因子的份子胶降解剂
▲作者:PAMELAY.TING,SNEHABORIKARetal.
▲链接:
https://www.science.org/doi/10.1126/science.adk6129
▲摘要:
镰状细胞病(SCD)是一种危和生命的常见疾病,可归因在β—血红卵白的遗传突变。医治性引诱胎儿血红卵白(HbF)可以改良疾病并发症,是以被紧密亲密存眷。但是,平安有用的HbF小份子引诱剂依然不明。
我们报导了WIZ转录因子的份子胶降解剂dWIZ-1和dWIZ-2,它们可以在红母细胞中增进HbF的发现。表型挑选显示WIZ是一种之前未知的HbF按捺因子。WIZ的药理学降解在人源化小鼠和食蟹猴中具有杰出的耐受性,同时可以在二者中引诱HbF。这些发现使得WIZ降解剂成为一种全球可和的SCD医治策略。
▲Abstract:
Sicklecelldisease(SCD)isaprevalent,life-threateningconditionattributabletoaheritablemutationinβ-hemoglobin.Therapeuticinductionoffetalhemoglobin(HbF)canamelioratediseasecomplicationsandhasbeenintentlypursued.However,safeandeffectivesmall-moleculeinducersofHbFremainelusive.WereportthediscoveryofdWIZ-1anddWIZ-2,moleculargluedegradersoftheWIZtranscriptionfactorthatrobustlyinduceHbFinerythroblasts.Phenotypicscreeningofacereblon(CRBN)–biasedchemicallibraryrevealedWIZasapreviouslyunknownrepressorofHbF.PharmacologicaldegradationofWIZwaswelltoleratedandinducedHbFinhumanizedmiceandcynomolgusmonkeys.ThesefindingsestablishWIZdegradationasagloballyaccessibletherapeuticstrategyforSCD.
Evolutionandhost-specificadaptationofPseudomonasaeruginosa
铜绿假单胞菌的进化和宿主特异性顺应
▲作者:AARONWEIMANN,ADAMM.DINANetal.
▲链接:
https://www.science.org/doi/10.1126/science.adi0908
▲摘要:
人类细菌病原体铜绿假单胞菌会在具有潜伏免疫缺点或囊性纤维(CF)等布局性肺部疾病的人群中引发多重耐药传染。我们的研究注解,在程度基因获得的驱动下,少数情况分手株已成为主导的风行克隆株,这些克隆株在曩昔200年中顺次呈现并经由过程全球传布收集传布。
这些克隆株在传染CF或非CF个别方面表示出分歧的内涵偏向(与巨噬细胞内可以或许存活的特定转录转变有关);履历了多轮趋同的、针对宿主的顺应;并终究掉去了在分歧患者群体之间传布的能力。我们的研究成果注释了铜绿假单胞菌的致病进化,并强调了全球监测和交叉传染预防对避免将来呈现风行克隆株的主要性。
▲Abstract:
ThemajorhumanbacterialpathogenPseudomonasaeruginosacausesmultidrug-resistantinfectionsinpeoplewithunderlyingimmunodeficienciesorstructurallungdiseasessuchascysticfibrosis(CF).Weshowthatafewenvironmentalisolates,drivenbyhorizontalgeneacquisition,havebecomedominantepidemicclonesthathavesequentiallyemergedandspreadthroughglobaltransmissionnetworksoverthepast200years.TheseclonesdemonstratevaryingintrinsicpropensitiesforinfectingCFornon-CFindividuals(linkedtospecifictranscriptionalchangesenablingsurvivalwithinmacrophages);haveundergonemultipleroundsofconvergent,host-specificadaptation;andhaveeventuallylosttheirabilitytotransmitbetweendifferentpatientgroups.OurfindingsthusexplainthepathogenicevolutionofP.aeruginosaandhighlighttheimportanceofglobalsurveillanceandcross-infectionpreventioninavertingtheemergenceoffutureepidemicclones.
特殊声明:本文转载仅仅是出在传布信息的需要,其实不意味着代表本网站不雅点或证实其内容的真实性;如其他媒体、网站或小我从本网站转载利用,须保存本网站注明的“来历”,并自大版权等法令责任;作者假如不但愿被转载或联系转载稿费等事宜,请与我们联系。